Francesco Totti missed the derby and is still out of action after a thigh strain, so Erik Lamela could receive his Roma debut.
Roma coach Luis Enrique said: "We started out with Totti and Miralem Pjanic, while Lamela is also a great player and it is possible to field all three at once. A team has to be balanced, but quality makes things easier.
"I have five players who can act as striker and only 11 players in total can start a game. I am very happy to have someone like Marco Borriello, or indeed the other forwards, at my disposal."