A Champions League tie played in England is one of 680 matches across the world investigators say was fixed, reports BBC Sport.
European police did not reveal the identity of the match they believe was corrupt in England.
But Europol did say that they had uncovered an organised crime syndicate based in Asia that was co-ordinating the operation.
Some 425 match officials, club officials, players and criminals are suspected of being involved.
Asked specifically about the allegations surrounding the Champions League tie held in England, Rob Wainwright, director of Europol - the European Union's law enforcement agency, declined to identify the match because of "on-going judicial proceedings".
However he did say it happened in the last three to four years, adding: "The focus has been on other countries, not the United Kingdom. However we were surprised by the scale generally of the criminal enterprise and just how widespread it was.
"It would be naive and complacent of those in the UK to think such a criminal conspiracy does not involve the English game and all the football in Europe."
A Uefa spokesman said they would co-operate with the investigation. He said: "We will be liaising with Europol in relation to any reports of match fixing in European competition."