The Gunners teenager was overlooked for Fabio Capello's squad for September's Euro 2012 qualifiers but Pearce is of firm belief that returning to the U21s is not such a bad thing for the former Bolton loanee.
"Jack's had the experience of an international cap with the seniors and his development will come," Pearce said.
"Like Theo Walcott, I think having the experience of playing with the Under-21s and seniors will be a help to him and is something he will have to come to terms with.
"He shouldn't feel disappointed that he's been in the senior squad and then come back to the Under-21s.
"That's the mentality he has to come to the squad with."
Wilshere's Arsenal teammate Henri Lansbury was included in the squad along with Liverpool's Martin Kelly, Chelsea's Michael Mancienne, Manchester City's Micah Richards, Manchester United's Chris Smalling, Aston Villa's Marc Albrighton and Newcastle United's hat-trick hero Andy Carroll among others.