Drogba looked out of sorts against the Greeks in his first game for Chelsea since returning from the African Nations Cup.
Avram Grant now has a fully-fit squad to choose from for the first time since he took charge and the Ivory Coast striker admitted that "is a big problem for the manager" as he tries to settle on his best side.
Drogba said: "We had a difficult game and could have done better. The good thing is we have a second game at home and have to improve if we want to beat Olympiacos.
"I am looking forward to playing with Nicolas Anelka but I am just happy to be back and playing with my mates.
"I hope we can do great things but don't forget the other players. We have a big squad and I hope everyone will be committed and give everything for what we want to achieve."