The Germans host the Gunners at Signal Iduna Park in the fourth Champions League fixture of the campaign and Klopp is expecting another difficult even though his side saluted 2-1 in London last month.
"It will be an intensive match with many duels," he told reporters. "At this level, neither team can surprise the other.
"Small things make a difference, such as when [Santi] Cazorla hit the bar [at the Emirates]. If Arsenal are stronger at [our] home it is because we let them be."
Klopp added that defender Mats Hummels is likely to miss with injury while Marcel Schmelzer should be right to take his spot in the line-up.
"At the moment, it seems that Mats will not play," he said. "With Marcel, it looks a lot better."
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