Akinfeev is a target for United boss Sir Alex Ferguson, who spoke glowingly of the Russia international after their win in Moscow a fortnight ago.
"I have heard the speculation but it is just talk, nothing else," he said.
"I cannot look at this match from a personal perspective. The career of every footballer grows from such games.
"We are playing a legendary team in a legendary stadium. It will be an inspirational game, the most important in our careers."