The Chelsea midfielder is expected to start when the Three Lions meet Ukraine in Kiev which will mark his milestone that has taken almost 15 years to cultivate.
"All things being equal, Frank will play and start the game tomorrow and win his 100th cap," Hodgson said at a press conference.
"I'm happy to be part of that. I don't think there will be many players who will play for England for two or three years, let alone 14 years.
"Fourteen years is a long time to be representing your country. We don't have that many international matches, so I think people who want to play 100 games for their country have to play for a team that wins major international tournaments and play for a very long time."
Lampard will become the eighth player to reach 100 English caps joining current teammates Steven Gerrard and Ashley Cole as well as Billy Wright, Sir Bobby Charlton, Bobby Moore, David Beckham and Peter Shilton.