The European champions are set to take on the MLS All-Stars at PPL Park on Wednesday night and the Brazilian centre-back is excited about the possibility of playing against the former Arsenal and Manchester United stars.
"Those two," he told MLSsoccer.com when asked who he is keen to play against.
"They are great players that not just I know about, but the whole world knows them. I hope to have the opportunity to play against them in the next game."
And Luiz also had some kind words to say about the state of the game in the USA, suggesting that it is improving rapidly with a strong name on the world stage.
"Soccer in America is growing and today you have a lot of players of a different quality, when no one believed in soccer before," Luiz added.
"Today, MLS is recognized as being at a different level and it has a different image in the world."