Milovan Rajevac stepped down from the role earlier this month after leading the Black Stars to the quarter-finals of the World Cup in South Africa.
The 42-year-old Desailly, who was born in the Ghanaian capital Accra but opted to play international football for Les Bleus, has declared his interest in succeeding Rajevac and believes he has the necessary backing.
"Nothing is done. All parties seem okay on my project, from the minister to the president of the federation, but we must wait," he told L'Equipe.
"I'm surrounded by a team that includes English speakers, because I do not want to make some errors from the past.
"The Ghana team has a very good structure. I'm available. We must now talk about money and how exactly it would work.
"Here in the English-speaking countries, there are many committees who have to meet. We'll see but everyone seems to agree on my candidacy."