Lloris, 25, cost Spurs £12million from Lyon but Lollichon reckons the French No 1 will struggle to adapt to the English game.
Lollichon said: "Premier League strikers are far more aggressive in the penalty area and the quality of crossing is better.
"Keepers need good timing to cancel out the aggression of opponents at set-pieces.
"Some of the best strikers in the world are here and Hugo will come across those who are typically British and very hard to play against, like Grant Holt.
"His talent isn't up for discussion but sometimes it's going to be very hard for him."