Manager Roberto Di Matteo has confirmed he will make changes, one of which will almost certainly see Fernando Torres recalled.
Cech said: "We have almost everybody fit so we can rotate the team.
"It is a massive game for us against Arsenal because we need to reach the Champions League spot.
"It is always hard to manage everything around, but Barca have the 'Clasico' as well, so maybe there is the advantage in that we have a massive game, they have a massive game and we both have to manage that.
"Who's going to do it better? Let's see."