Villas-Boas was keen to play down the impact he or Ferguson would have on Sunday's proceedings.
"I don't think it can be reduced to two managers taking on each other," he said.
"Our importance in the game is minimal.
"It's for the players to exploit their talents and enjoy their game."
Villas-Boas had only just turned nine when Ferguson took charge at Old Trafford and did not become aware of the 69-year-old's incredible exploits until much later.
"I don't even remember how old I was when he took charge," Villas-Boas said.
"I was in love with my Porto and didn't have enough football knowledge to extend myself.
"My love for the Premier League started when it started casting itself wider a bit more."