Mourinho conceded defeat in the Barclays Premier League title race after his side's 1-0 defeat by Crystal Palace last week, while Chelsea were beaten 3-1 by Paris Saint-Germain in the first leg of their Champions League quarter-final on Wednesday.
He said: "The Champions League is not over, clearly. It's not over: far from it. If a player doesn't believe it's not over, it's better to stay at home. If any supporter thinks not possible, better to stay at home and watch Dortmund versus Real Madrid on the television. It's not over.
"In relation to the Premier League, we have six matches to play. The moment we don't want to give everything to win all matches, we're not good professionals. I won't accept that about me or my players.
"I'm not going to rest eight players against Stoke because we have no chance and can beat PSG. I'm saying go for it, go for the six matches and try to win them."
For breaking stories and all the great banter like us on Facebook: facebook.com/tribalfootball