Anelka was somewhat wasted out on the left of a supposed three-pronged attack, but which often left Drogba isolated and creative England man Joe Cole was kept on the bench until extra-time.
But the 52-year-old insisted it was a strike partnership which can deliver.
"It was the first game they played together. I think it will be a good combination," said Grant.
"We wanted to play Anelka on the side because he's a creative player and quick. That's what we wanted from him.
"Today was not an easy game for them to do their best."
Grant added: "It is not a casino - there is no gamble in football.
"They can play together, no question. You can't pick players like them and say it's a gamble."