The Spaniard has missed the Blues last two matches, including Sunday's 3-0 victory over Newcastle in the fourth-round of the FA Cup, with a hamstring complaint.
Speaking after the match, Blues boss Antonio Conte was asked if Morata would feature on Wednesday.
"Probably," said Conte. "He is going to start training from tomorrow, but not with us. After a period of rest, tomorrow he will start training.
"After an injury of this type, he needs a bit of time to recover, but at the same time we hope to have this player very soon."