Benitez is drawing on his experience with Liverpool to lift his players.
The Reds faced elimination in 2004. Needing to beat Olympiakos by two goals they went 1-0 down at Anfield.
But Benitez's men equalised then scored twice in the final 10 minutes to start a journey that ended in glory in Istanbul six months later.
Benitez said: "Special things can happen in the Champions League and if we go through I can guarantee you there will similar emotions (to 2004).
"I am confident we can go through. Everybody is talking about Shakhtar's players so they have to show they are really good players."