Hazard's hamstring injury is set to keep him out of their clash with Benfica.
"It will be a big blow if he's missing," Lampard admitted to the London Evening Standard. "He's an absolutely fantastic player and he has come into his own.
"He made the goals for me [against Aston Villa] which is what he does all the time for us as a team. He beats people, he puts the ball on a plate, he has a magic about him. I love playing with him so I just hope he will be fit."