"Real Madrid looks like a powder keg and is liable to blow up," he told Catalan station COMRadio.
"The situation at Real Madrid is one of revolt. There are unnecessary confrontations.
"The current president's policy does not promise anything else. The need to prove that one is smarter, taller and more handsome than anyone brings problems."
He insisted, however, that he would not be tempted to return to the Bernabeu, having stood down from the post in January 2009.
"My time at Madrid is over," he continued. "It has not crossed my mind to go back."
In a move likely to further antagonise his former employers, Calderon admitted that Barcelona are currently "teaching a permanent lesson in how to play football".
He added: "I do not remember seeing such a complete team. In Barca they opted for a model after the arrival of (Johan) Cruyff. Madrid have not been so patient."