Defour was regarded as one of the finest young midfielders in Europe back in 2009 and a host of clubs including United were very keen on making a swoop for the Belgian international at the time.
Evidently a transfer to Old Trafford did not occur and now the Burnley star has gone on to explain that injury issues meant that he could not join a club such as United, despite both parties keen on facilitating the deal.
Defour told Sky Sports: "Before my injury it [a United move] was one of the possibilities, because I knew they were following me but then came that severe injury and that was quite a hard one from me.
"It was an open fracture of my foot and I was really down because, for the first time, I could have played in the Champions League and then three days before I broke my foot so I was really down.
"It was difficult to find my form before my injury to have the level of a club like Manchester United."