Outside of Tom Huddlestone's man-of-the-match display there were first goals of the season for captain Robert Koren, who netted twice from close range, Matty Fryatt and George Boyd.
Ahmed Elmohamady, meanwhile, set the ball rolling by opening the scoring three minutes into the second half.
Hull had scored just nine times in their previous nine games at the KC Stadium and Bruce was happy to bask in a rare prolific day.
"It was one of the great days that we will remember for a long, long time," he said.
"In my experience it doesn't often happen that you go and win 6-0 in the Barclays Premier League.
"It was quite incredible. We got the first one and then the floodgates opened, which doesn't happen very often at this level."
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