Goldson is poised to make his Premier League debut, only nine months after heart surgery.
"Connor has trained very well," said Brighton manager Chris Hughton.
"He was unfortunate last season to miss a large period but he's been ready for some time, and he played for the Under 23s last week.
"That's why those not in the side have to train hard and be prepared. When the opportunity comes you have to be ready for it."
Hughton added: "The best news was that it was a condition picked up by our scanning process and that he has made a 100 per cent recovery.
"He will look back on the football he has missed appreciating what he has gone through and looking forward to getting back playing.
"He's a good player and we are delighted with his progress."