Goldson, 25, had preventative heart surgery in February after routine screening uncovered "a possible risk factor".
Hughton praised the centre-back as he played the full 90 minutes on his Premier League debut and was given man of the match by the stadium announcer.
"Someone who has not played for that period of time, to put in that kind of performance speaks volumes for him," Hughton told Match of the Day.
"The scare and what he went through last season is out of the way now.
"He has waited a long time to get the opportunity to play - everyone is so delighted for him."