Lanzafame has signed on-loan with the Serie B club to the end of this season.
"I can't wait to get started with Brescia," he told SportItalia. "I already know a few people in the side and am at the Coach's disposal."
The 23-year-old was expected to play a bigger part in the Juventus season, but found himself on the bench or in the stands.
"It was (coach Gigi) Del Neri's decision. The Coach and the club decided to release me. I'm happy anyway, as I feel that Brescia can escape relegation."