Holden has come on as a second-half substitute in the US's last two games, but he says he's ready for more if needed.
"I'm ready to go 90 if called upon," Holden said. "[Head coach Jurgen Klinsmann] spoke to us before the last game and managing minutes with the artificial surface there and given our history with knee injuries.
"To come on in the second half and have an impact was something I wanted to do, and the team got a good result, a solid performance. Now, we really need to make sure we have a good performance against Cuba."