The Gunners travel to Ewood Park on Sunday with memories of the bitter defeat at the hands of Rovers still fresh in their minds.
After a goalless draw at the Emirates Stadium, Cesc Fabregas made insulting remarks to Hughes' face and Arsenal manager Arsene Wenger was also uncomplimentary about Blackburn following their 1-0 win in the replay.
He said: "We won through last season in the Cup after a great strike from Benni McCarthy.
"People seem to forget a few weeks before that we had been beaten by six goals at the Emirates. We went back there with a gameplan, got the job done, Benni was available for the replay and he made the difference."
Asked about the responses of Fabregas and Wenger, the Rovers boss added: "In fairness to the young man he apologised afterwards in the dressing room and that was the end of it as far as I am concerned.
"And when managers get beat they tend to look at the game from their point of view and I'm guilty of that as well. After you have had a painful defeat it can be difficult to give credit to the opposing team and you have to recognise that."