Karim Benzema struck for Real Madrid on French soil in their 1-1 draw at Champions League opponents Lyon.
Bafetimbi Gomis struck a late equaliser for Lyon but Real will be favourites to progress to the Champions League quarter-finals for the first time in seven years thanks to Benzema's away goal.
Benzema, who joined Madrid from Lyon in 2009, scored just seconds after coming on as a 64th-minute substitute to put Madrid ahead in this last-16, first leg tie.
Madrid could not hold on to that advantage with Gomis volleying home in the 83rd minute, but Jose Mourinho's men will fancy their chances in the second leg at the Bernabeu, where they have won their last 22 competitive games.
