"Are we scared of Arsenal?" Benitez asked on Tuesday, before answering his own question with an emphatic: "No."
"When we play in Europe we have a lot of confidence and playing against Arsenal we beat them 4-1 at Anfield last season.
"This season we drew 1-1 and we had big problems because Torres was injured. We played 45 minutes with him not fit, and after we had a problem with Alonso.
"I think we can beat them if we do our job and we work as hard as we were working before."
Wednesday's meeting at Emirates Stadium is the first of three games between the pair in a week and Benitez believes knowing each other's game inside out will not prove to be an advantage for either side.
"I think it's the same situation for both teams," said Benitez. "We had the same problem with Chelsea in the last three years and now in a few days we will play three games against Arsenal, so I think it's more or less the same situation for both."