The midfielder is currently on African Cup of Nations duty with Mali and Benitez said the player could leave before the end of the January transfer window.
"We know that they (Juventus) are interested in Momo but we need to wait until the end of the transfer window and we need to be calm," he added.
There are two Spanish clubs and two Italian clubs also interested in Momo and we will try to do the best for the club."
When asked if he thought Sissoko would leave this month, Benitez told the clubs official website: "Yes I think so. It could be a possibility but it depends on the other teams if they push hard or not."