Barcelona president Josep Maria Bartomeu has not denied they made an attempt for Isco over the summer.
The Real Madrid midfielder confirmed contact with Barca last week at his new contract signing ceremony.
Asked about the claims, Bartomeu could not deny Barca made a move for the Spain international.
"Isco? I do not know if there have been any contacts," he told TVE.
"But I imagine that the leaders are doing their job and contact a lot of players..."