However, he has struggled to hold down a first-team spot at Old Trafford and would welcome the opportunity of regular football back in his homeland.
Barcelona are keen to launch a summer rebuilding programme after ending the 2007/08 season empty handed and see Pique as a long-term option at the heart of their defence.
"Things are at an advanced stage," Barca's sporting director Txiki Bergiristain confirmed.
"I can't deny that he is one of the players we're interested in, but he is involved in the Champions League final so things are on hold."