The 30-year-old's first-half strike put Spurs on course for a 2-0 win in the Europa League and moved him one goal behind Martin Chivers' long-standing European record of 22.
"We have to judge recovery and the fact that JD was involved today and Soldado wasn't," Villas-Boas said. "Everything will come into consideration.
"We have been extremely happy with the performances of both. It is a question of deciding what is best for the team.
"It was another great goal, a great finish. It's really good to see him out there again doing extremely well whenever he's given the opportunity.
"He is a great professional, has a great attitude and now he's only one off Martin Chivers so it's a real great achievement for him.
"I think he has the ambition this season to go even further up the ladder in this record tally behind Martin Chivers and as an all-time goalscorer so I think that plays highly in his motivation, definitely."
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