The two teams meet on Thursday night.
Gasperini said, “Europe is a novelty for us and we'd like to get off to a strong start. The fact this is one of the toughest groups of the tournament isn't an alibi, but it is an undeniable difficulty.
“Everton are a typically English side, very physical. When you face sides that finish sixth in the Premier League, it's like Milan, Inter, Lazio or Fiorentina. We know it's tough, but we want to play to the best of our abilities."