The Gunners will be thirsting for revenge after their 8-2 humiliation at Old Trafford in August — their heaviest-ever Premier League defeat.
Russian midfielder Arshavin said: "They are very strong but at home we can beat everyone too and I hope we will do it.
"If we play well we don't mind what form they are in.
"I don't think we play differently at home, we just try to play in our own style.
"Of course, at the Emirates you feel the supporters more and teams are more scared. I think it's easier to play at home.
"Man United started the season very well.
"They seemed very far from everybody else but at the moment they are not. Manchester City are above them."