Oxlade-Chamberlain says Sir Alex Ferguson couldn't go on forever.
He said: "I don't know what the managerial change will bring for United.
"It doesn't change they way we approach things. Sir Alex Ferguson was an amazing manager for so many, but at some point he had to retire - he couldn't have stayed in the game all of his life.
"So, in that sense it does bring a certain amount of uncertainty, but that's only for fans and football followers - but not for me or my team mates."