The French tactician believes all players who leave Arsenal understand later on that their decision was wrong and he thinks the same would happen with the skipper.
Wenger used veteran defender Sol Campbell as an example of a player who left the club then came back after he realised he had made a poor choice.
"All of the players who have left wanted to come back so they are not as unhappy as they sometimes look," Wenger said.
"When Sol had achieved what he wanted to with us, he was a little bit in no man's land for a while.
"But now he is mature and very clear in his head that he wants to go as far as he can.
"I cannot stop talk about Fabregas but some try to be specialists in making players unhappy."