Szczesny says Arsène Wenger's side enough quality to respond positively after defeat to Aston Villa.
"It is not an easy draw - it is never easy to go to Turkey in front of a very enthusiastic crowd," he told Arsenal Player.
"It will be very tough but we are a confident team and if you want to play in the Champions league we should be going to Fenerbahce and getting a win.
"I wouldn't say the atmosphere affects the players but you enjoy it that bit more when the crowd is buzzing and it is so intense. I love it. You try a little bit harder when the fans are on top of you."
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