A fatal dash from his line cost Arsenal the second goal, albeit Cristiano Ronaldo's tap-in also coming courtesy of a lightning United move.
Several more rushes of blood when Almunia went AWOL from his six-yard box spread confusion in an otherwise robust defence.
When he does he might rue his decision to stick by Almunia ahead of Jens Lehmann, a player with vastly more experience if one also not unaccustomed to the odd aberration.
Wenger explained: "Lehmann was injured and Almunia has done extremely well since, 10 games on the trot. I didn't want to disturb the side.
"Until now, he has done very well. I believe in sticking with one goalkeeper. You cannot tell him: 'No matter how many mistakes you make, you'll always be my goalkeeper.' But you have to give him at least two games."