Stadion FK Partizan will be at boiling point come kick-off, as The Gravediggers look to extend Arsenal's record of failing to win away in the Champions League since last September.
The Serbians, though, have something of a chequered history of crowd trouble and were thrown out of the 2007/08 UEFA Cup for clashes in a qualifying tie against Zrinjski Mostar - while in September last year, a Toulouse fan died in hospital after being injured following violence in a bar ahead of the two sides' Europa League tie.
Indeed, Partizan went as far as issuing a plea for calm on their own website, declaring "this is our chance to wipe out ugly traces of the recent past and we shouldn't miss this opportunity."
Wenger, though, is confident the game can pass without incident.
"We are always inside the stadium, so I do not know what is happening outside, I leave that to UEFA and to the Serbian authorities. I am sure they will do that very well," he said.
"Serbia is a traditional football country and I believe it will be very passionate because they are very passionate football people."