Wenger, whose side sealed their passage to the last 16 with a 2-0 win over Standard Liege at the Emirates thanks to goals from Samir Nasri and Denilson, insisted he was not surprised Liverpool were eliminated from the competition.
Wenger said: "You always favoured Fiorentina at home against Lyon, who are not on an especially good run, to qualify for the first time in their history.
"I thought it would be difficult for Liverpool to qualify.
"They can, of course, respond well and do well in the Europa League."
When asked if Wenger was glad his Premier League rivals were out, the Frenchman replied: "Frankly, no. Anyway, If Liverpool are out, another big team is in. We cannot play against them in the next stage anyway."