Arsenal boss Arsene Wenger admits defeat at Tottenham will be a huge blow to their top four hopes.
Wenger accepts there are no longer any margins for error if his team at to secure another top-four finish.
"It is still open, but I am realistic and we cannot drop points," he said.
"One or two of the other teams will always win over the weekend. If we drop points we can fall quickly behind.
"So there are two things we cannot do - drop points and also speculate over the weaknesses of our opponents because that can be deadly as well."