However, the Dutchman - just back to fitness having been out since January with a broken metatarsal - was able to quickly rejoin his team-mates for the presentation ceremony.
"Physically it was a tough game. What you can see is the spirit is strong in the team and that everybody works for each other. That is very positive," Wenger told Sky Sports.
"It has been a perfect pre-season to start the championship."
However, the Arsenal manager continued: "I was very disappointed with some of the challenges.
"I think some players were a little bit overboard, but we kept our nerve.
"Some ways, the fact that you know you would be suspended in England if you over-react here helps us.
"I am proud of them because you cannot let everybody kick you without showing that the team is ready to respond. There was no over-reaction."
Van Persie is likely to be closely monitored ahead of the clash with Fulham on Sunday following a crunching challenge from his Holland team-mate John Heitinga.
Wenger said: "I was very disappointed by this tackle, but he looks all right at the moment.
"Today we had Gilberto out in midfield, [Alex] Song, [Abou] Diaby and [Cesc] Fabregas did not play.
"So we have plenty of quality players, and the pre-season tells you that we have a big squad."