The Argentine is expected to sign for Arsenal.
Former Tottenham boss Ardiles said: "Can Higuain be as good as Van Persie? Of course he can, that's how good Higuain is.
"You remember when Van Persie arrived he was not exactly, immediately, the best player, it took a bit of time. But he was younger, now Higuain is much more experienced.
"Higuain is a top player. He will always score goals. He likes to be in the box all the time and he works hard for his team, wherever he goes he's going to be great for the team he's joining."