Real Madrid have been rocked by injury to three fullbacks during international week.
Brazilian Marcelo broke a metatarsal while training for his country's friendly against Japan in Poland last week, while Fabio Coentrao was forced off after just 20 minutes of Portugal's clash with Russia.
Tuesday night's draw between Spain and France could also have ramifications for Jose Mourinho as his first-choice right-back Alvaro Arbeloa, who could also have provided cover on the left, limped off early in the second half before France forward Karim Benzema suffered a late knock to his knee.