Juan Antonio Anquela has been sacked as Granada coach.
Monday's 3-0 loss away to Sevilla left the Andalusians just two points above the bottom three ahead of a daunting run of fixtures that includes meetings with Real Madrid and Barcelona in the next three matches.
"The board of Granada CF has...removed the coach Juan Antonio Anquela," said a statement on the club's website.
"The club is now working to hire a new coach. Granada CF thank Anquela for his involvement and work and wish him every success in his future career."