The Dutch title-holders host the Premier League champions in their third group stage fixture of Europe’s premier club competition and de Boer has made it clear that he is not running scared from City’s firepower.
"If you want to stay in Europe after the winter break, whether in the Champions League or Europa League, we need a result tomorrow," said de Boer.
"We believe in it. The Real (Madrid) match (4-1 loss) was a poor match for us and in the Borussia Dortmund game we were unlucky. Tomorrow is different.
"Manchester City are a good team but we have a good team as well and we have faith in a good result."
De Boer added: "Manchester City are still at the top, with a lot of players who still play for their own national teams.
"Take the four strikers together and they still cost more than the annual turnover here.
"They have proved their qualities already and no matter who is playing for them they are always a tough team to play against.
"It is always difficult to put your finger on why they are not performing as they are in the Premier League.
"Everything can change suddenly but hopefully they are not going to hit that form here."