With teams dropping points in their last two outings, it is a vital match to get back to form.
Over the years, the Sky Blues have had the wood over the Reds with Sydney winning seven of 12 matches between the clubs.
Adelaide coach Aurelio Vidmar is determined to get closer to squaring the ledger.
“We need to turn it around and we probably couldn’t be in a better situation for us, we’ve lost a couple of A-League games on the trot and we don’t want to make it a third so we really need to roll our sleeves up and get a job done,” Vidmar said.
“I’m expecting a massive game from the players. They know the situation, they’ve worked really well this week so hopefully with those couple of days rest, it has given them a little bit of renewed energy so they can go out tomorrow with all guns blazing and try to get the three points.
“It’s going to be a really interesting game because they’re coming off a couple of poor results as well so in a way we’re in the same predicament so it will be like a mini final for both teams,” Vidmar added.
Adelaide welcomes back Young Socceroo Daniel Mullen along with midfielder Paul Reid, Robert Younis and Kristian Sarkies, the latter two having both scored doubles for the youth team last week.
Sasa Ognenovski makes his 50th A-League appearance, 38 of them being with Queensland Roar.
In the Sydney camp, Adam Casey and Robbie Middleby have been included in the squad but there is a major out due to the retirement of veteran Tony Popovic.