Seedorf believes they can make a statement by beating the defending champions.
"We will have a packed San Siro behind us, just as we did against Atletico Madrid. The lads really need it," he said.
"This is my first Milan-Juve as a Coach. I feel honoured and privileged to experience it at such a young age. For the team this is the chance to put in a great performance, build confidence and help us face the rest of the season in the best way.
"Antonio Conte has done a great job and I tip my hat to him. Since winning the title in the first season, Juventus have only improved. When you win the self-confidence grows and players get more accustomed to working together.
"I have never worked with Conte, but he certainly helped to renew Italian football. I consider him a very positive influence, like Vincenzo Montella at Fiorentina. I still have everything to prove and am trying to learn quickly.
"Serie A is the toughest League in the world precisely because every Coach is well-drilled in tactics. In terms of players the level of individual stars might've dropped because the money migrated elsewhere, but it's still a very high level."
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